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In the economy of every country, human resources are the key to improving the economy, in this study companies in Indonesia, especially in Bandar Lampung, are expected to be able to understand the right Talent Engagement process and the right strategy to attract talent from Generation Y and be able to manage human resources to be able to provide a sense of satisfaction at work. This study aims to determine the effect of work life balance and burnout on job satisfaction of Generation Y employees in Bandar Lampung, in this study using a sample of 140 respondents, with a total of 28 items of statements from 3 variables and using data collection techniques by distributing questionnaires via google form. , the results obtained were processed using the Statistical Program for Social Science (SPSS), with analytical tests, namely validity, reliability, and hypothesis testing, namely multiple linear regression, partial test, simultaneous test, and coefficient of determination. The results of this study are that work life balance partially has a positive and significant effect on job satisfaction of Generation Y employees in Bandar Lampung, partially burnout has a negative and significant effect on job satisfaction of Generation Y employees in Bandar Lampung, and work life balance and burnout simultaneously have a significant effect to the job satisfaction of Generation Y employees in Bandar Lampung.