Currently the world is faced with the Covid-19 pandemic, including Indonesia. The Covid-19 pandemic has temporarily stopped almost all activities, including the world of education, which is forced to carry out online or online learning, especially in universities, this step was taken to reduce the spread of covid-19 in Indonesia. Online lectures have various impacts including on the ability of students, especially midwifery students, in terms of Ante Natal Care (ANC) practical skills. One of the reasons is that students' lack of understanding of ANC skills is because learning about ANC theory is provided through online. Learning online is not easy. Difficulties arise not only in terms of skills in using technology, but by increasing a large quota and not having a laptop. This study aims to determine the effect of online learning on the level of understanding and skills of midwifery students. The method used is descriptive with a quantitative approach. The population in this study were students of midwifery at the Tahirah Al Baeti Bulukumba Midwifery Academy. Sampling was done by random sampling. The sample criteria are midwifery students who actively participate in online learning. The research questionnaire uses Google Form through online media. Analyzed using the Chi-Squaretest to determine the relationship between the two variables. Data analysis was performed using SPSS. The results of the analysis show that online learning that is carried out is obtained by students who do not agree with online learning (83.3%) because of the obstacles in using learning applications, namely students do not have a quota (47.9%) and difficult internet networks (41.7%) . Meanwhile, students tended to experience a decrease in their skills (50.0%). It can be concluded that there is an effect of online learning and on student ANC learning abilities and skills. Criticism can appear in various stages of lectures, so it is important to conduct research related to differences in the degree of knowledge of early and late students.